Facet joint biological therapy

Facet Joints

Biological therapy

What is Biological therapy?

Our blood is made up of 93% red blood cells, 6% white blood cells, 1% platelets and plasma. Platelets are best known for their function of blood-clotting to stop bleeding. Platelets, however, are much more significant than this, as human platelets are also a critical component in injury healing.

Biological therapy for musculoskeletal conditions

Biological therapy, commonly referred to as Biological therapy, is an autologous blood derivative- it is human blood that is spun down and separated producing a concentration of platelets above normal values. Platelets are the clotting cells of our blood, but they also have great potential in enhancing healing of muscle, tendon, and ligaments. Studies suggest that growth factors released by platelets recruit reparative cells, may augment tissue repair, and accelerate soft tissue healing.

What does the process of Biological therapy involve?

  • After assessing you, a nurse will take your blood (like a standard blood test), which will be spun in a centrifuge to isolate the plasma component.
  • Biological therapy is activated under a light. Then the Biological therapy is injected directly into the site of injury. The process will take around 45 to one hour.
  • Local anaesthetic is injected 15-20 minutes before or at the same time with Biological therapy injection depending on the injury.

How does Biological therapy work?

The growth factors and platelets in the plasma promote cells to multiply and form new tissue accelerating and enhancing the healing process.

Biological therapy contains a much higher concentration of platelets than normal blood. This means that higher concentrations of growth factors are being released into the injured area.

When compared to cortisone injections, Biological therapy injections hold better results and last much longer. While the effects of cortisone are rapid, they are often followed by a decline in condition. Biological therapy shows slower but greater long-term improvement and less injury recurrence.

What can be treated with Biological therapy?

  • Osteoarthritis
  • Muscle, ligament, and tendon injuries (including tennis or golfer’s elbow)
  • Degenerative knee conditions
  • Facet joints Arthritis
  • Bursitis
  • Cosmetic (hair, face)
  • Rotator cuff
  • Gynaecological conditions

At Melbourne Arthritis specialist Centre we focus on musculoskeletal application of Biological therapy therapy.

Preparing for your Biological therapy appointment

Please drink plenty of water and eat healthily prior to treatment. Avoid smoking if possible.

After your Biological therapy treatment

Following the first Biological therapy treatment, you will be provided with exercises and advice specific to your injury/problem area.

Improvement will be a gradual process over the days to weeks following your treatment.

Treatment frequency

Frequency and number of treatments will depend on how severe the condition is. For chronic joint injuries such as osteoarthritis, we recommend a course of three sessions, one week apart, followed by annual top up sessions.

For soft tissue injuries such as tendon tears, treatment involves three injections, two weeks apart.

Please note

As Biological therapy is taken from your own blood, there are no risks of disease transmission or allergic reactions.

Sometimes Biological therapy may aggravate the inflammatory response, causing a temporary increase in pain and swelling of the injured area. There may also be a local pressure effect from the injection of the fluid. These effects should subside within a few hours to days. If pain is severe, contact the doctor.

For more information, please contact our friendly front desk on 98701400 or go to www.Melbournearthritis.com.au

Facet joint arthritis therapy with Biological therapy

What are your facet joints?

They’re the cartilage-lined links between your back bones, there are two between each vertebra. They enable your back and neck to flex smoothly so you can bend.

Facet Joints

What is facet joint syndrome/osteoarthritis?

It is pain caused by the aging process, which often leads to the facet joints becoming enlarged. Like most back pain, it can be made worse by lifting badly, or if you’re inactive or overweight.

What are the symptoms?

Pain around the affected joints, especially when turning, twisting or straightening. It’s often sore or stiff first thing in the morning. There’s also a chance it can cause discomfort, numbness or tingling in your buttocks and thighs. If the facet joints enlarge sufficiently to ‘trap’ nerves, then pain – often called sciatica – can radiate down your leg.

What is the next step?

As well as an expert consultation with a specialist on your symptoms and advice on the best way to relieve your pain, we offer both traditional and innovative therapies. The first step is to book a consultation for a thorough assessment. Please call 98701400 and speak with our Admin team.

Biological therapy Therapy for Facet joints

This is an effective and well-researched procedure that’s a potential alternative to surgery. It takes advantage of the blood’s natural healing properties to reduce pain and improve joint function. It uses a specially concentrated dosage of platelets prepared from your own blood to repair damaged cartilage, tendons, ligaments, muscle and bone. Patients usually see their symptoms improve in one to two weeks of having the injections.

After written consent, our Nurse Natasha takes your blood and put it in the special Biological therapy centrifuge and after 8 minutes we harvest the Biological therapy form the blood. Then patient will be positioned prone and after Prep and Drape, Mr Jithoo gives local anaesthetic around facet joint area skin. Then, He Injects Biological therapy into the facet joints and surrounding area under guidance of ultrasound machine. The patient will then be monitored for 30 minutes for safety measure and needs to be going home with a support.

Patients need to avoid extreme activity for 48 hours and this could be repeated in 1 to 2 months if needed.

Facet Joint Biological therapy Injection relative RCT Research

  1. A Prospective Study Comparing Biological therapy and Local Anesthetic (LA)/Corticosteroid in Intra-Articular Injection for the Treatment of Lumbar Facet Joint Syndrome.

    Wu J, Zhou J, Liu C, Zhang J, Xiong W, Lv Y, Liu R, Wang R, Du Z, Zhang G, Liu Q.Pain Pract. 2017 Sep;17(7):914-924. doi: 10.1111/papr.12544. Epub 2017 Feb 22.PMID: 27989008 Clinical Trial.

    OBJECTIVES: To compare the effectiveness and safety between autologous Biological therapy (Biological therapy) and Local Anesthetic (LA)/corticosteroid in intra-articular injection for the treatment of lumbar facet joint syndrome. METHODS: Forty-six eligible patients with …

    Read More

  2. A New Technique for the Treatment of Lumbar Facet Joint Syndrome Using Intra-articular Injection with Autologous Platelet Rich Plasma.

    Wu J, Du Z, Lv Y, Zhang J, Xiong W, Wang R, Liu R, Zhang G, Liu Q.Pain Physician. 2016 Nov-Dec;19(8):617-625.PMID: 27906940

    SETTING: The outpatient clinic of a single academic medical center. METHODS: Total 19 patients with lumbar facet joint syndrome (8 men, 11 women; mean ages: 52.53 6.79 years, range: 38 - 62 years) were enrolled to receive lumbar facet joint injection w …

    Read More

  3. Biological therapy for the Treatment of Low Back Pain: a Comprehensive Review.

    Urits I, Viswanath O, Galasso AC, Sottosani ER, Mahan KM, Aiudi CM, Kaye AD, Orhurhu VJ.Curr Pain Headache Rep. 2019 Jul 3;23(7):52. doi: 10.1007/s11916-019-0797-6.PMID: 31270622 Review.

    Biological therapy injections for sacroiliac joint-related pain are not an accepted or common treatment modality; the evidence for their efficacy remains to be seen outside of small RCTs and case reports. A small number of prospective trials have suggested there may be some benefi …

    Read More

  4. Regenerative Medicine for Axial and Radicular Spine-Related Pain: A Narrative Review.

    Desai MJ, Mansfield JT, Robinson DM, Miller BC, Borg-Stein J.Pain Pract. 2020 Apr;20(4):437-453. doi: 10.1111/papr.12868. Epub 2020 Jan 28.PMID: 31869517 Review.

    Eligible articles analyzed the therapeutic injection effects of Biological therapy (Biological therapy), prolotherapy, or mesenchymal signaling cells (MSCs) via intradiscal, facet joint, epidural, or sacroiliac joint delivery. ...CONCLUSIONS: Currently, there are l …

    Read More

  5. Do Regenerative Medicine Therapies Provide Long-Term Relief in Chronic Low Back Pain: A Systematic Review and Metaanalysis.

    Sanapati J, Manchikanti L, Atluri S, Jordan S, Albers SL, Pappolla MA, Kaye AD, Candido KD, Pampati V, Hirsch JA.Pain Physician. 2018 Nov;21(6):515-540.PMID: 30508983 

    CONCLUSION: The findings of this systematic review and single-arm metaanalysis shows that MSCs and Biological therapy may be effective in managing discogenic low back pain, radicular pain, facet joint pain, and sacroiliac joint pain, with variable levels of evidence …

    Read More

  6. Responsible, Safe, and Effective Use of Biologics in the Management of Low Back Pain: American Society of Interventional Pain Physicians (ASIPP) Guidelines.

    Navani A, Manchikanti L, Albers SL, Latchaw RE, Sanapati J, Kaye AD, Atluri S, Jordan S, Gupta A, Cedeno D, Vallejo A, Fellows B, Knezevic NN, Pappolla M, Diwan S, Trescot AM, Soin A, Kaye AM, Aydin SM, Calodney AK, Candido KD, Bakshi S, Benyamin RM, Vallejo R, Watanabe A, Beall D, Stitik TP, Foye PM, Helander EM, Hirsch JA.Pain Physician. 2019 Jan;22(1S):S1-S74.PMID: 30717500 

    Lumbar Epidural Injections Based on one high-quality RCT, multiple relevant moderate-quality observational studies and a single-arm meta-analysis, the qualitative evidence has been assessed as Level IV (on a scale of Level I through V) using a qualitative modified approach to the …

    Read More

  7. Comparative analysis of the effectiveness of Biological therapy therapy and facetoplasty in older patients with isolated lumbar facet syndrome: long-term results of a randomized controlled trial.].

    Byvaltsev VA, Kalinin AA, Okoneshnikova AK.Adv Gerontol. 2019;32(5):804-811.PMID: 32145173 Clinical Trial. Russian.

    The aim of the study was to conduct a comparative analysis of the long-term results of applying Biological therapy therapy and facetoplasty in patients of the older age group with an isolated lumbar facetsyndrome. The study included 159 patients over the age of 65 with symptomatic …

    Read More

  8. [Analysis of the clinical efficacy of Biological therapy therapy in the treatment of patients with isolated facet -syndrome of the lumbar spine].

    Byvaltsev VA, Kalinin AA, Okoneshnikova AK, Satardinova EE.Zh Nevrol Psikhiatr Im S S Korsakova. 2019;119(11):27-31. doi: 10.17116/jnevro201911911127.PMID: 31851168 Russian.

    AIM: To analyze clinical results of the surgical treatment of patients with isolated facet-syndrome of the lumbar spine using Biological therapy (Biological therapy) therapy for arcuate spine joints. ...Dynamic evaluation was made on average 18 months after surgery. RESULTS AND …

    Read More